Manchester United slumped to a limp defeat in Valencia as Paul Pogba's glaring miss and Phil Jones' own goal ensured they passed up the chance to win Champions League Group H.
United were already assured of qualification for the knockout stages, and a win would have taken them above Juventus, who were surprisingly beaten 2-1 by Young Boys of Switzerland.
But Jose Mourinho's side put in a poor performance and were well beaten by a team, 15th in the Spanish top flight, who named an experimental line-up as they were already certain of finishing third.
Carlos Soler pounced on Jones' headed clearance to strike home a fizzing low finish amid slack marking for Valencia's opener.
And Jones was badly at fault for the second after the break as he diverted a through ball past Sergio Romero from outside his own box, when the United keeper had left his line to claim the ball.
That disastrous error followed a remarkable miss by Pogba in the first half, when the France midfielder somehow stabbed wide from four yards out after Marouane Fellaini's knockdown at a corner.